Treating disorders associated with IL-20 receptor-mediated signaling pathway by blocking IL-20 receptor activity

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专利权人:

National Cheng Kung University

发明人:

Chang, Ming-Shi

申请号：

AU2011239520

公开号：

AU2011239520A1

申请日:

2011.04.15

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Treating a disorder (e.g., osteoporosis, renal failure, or diabetic nephropathy) associated with a signaling pathway mediated by IL-20 receptor with an agent that suppresses IL-20 receptor activity, e.g., an antibody that neutralizes IL-20 receptor via binding to IL-20R1, an antisense nucleic acid that suppresses expression of IL-20R1, a small molecule that inhibits IL-20 receptor activity, or a dominant negative mutant of IL-19, IL-20, or IL-24.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/