Unity Biotechnology, Inc.;Kythera Biopharmaceuticals, Inc.
发明人:
Serge Lichtsteiner,Nathaniel David
申请号：
US16436265
公开号：
US20190316109A1
申请日:
2019.06.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Polypeptides, viruses, methods and compositions provided herein are useful for the selective elimination of senescent cells. Method aspects include methods for inducing apoptosis in a senescent cell comprising administering to the cell a polynucleotide, virus, host cell, or pharmaceutical composition described herein. Other methods include expressing a pro-apoptotic gene in a senescent cell comprising administering to the cell the polynucleotide, virus, or pharmaceutical composition as described herein.
