The Government of the United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
MOSS, Bernard,WYATT, Linda,EARL, Patricia
申请号:
DK07874019
公开号:
DK2062023T4
申请日:
2007.08.24
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention relates to a method of stabilizing an insert in a recombinant vaccinia virus by disrupting a run of 4 or more G or C residues through a substitution that introduces a silent mutation in the run, the length of which is thereby reduced.