Disclosed are systems, methods, and devices (100) for sensing and analysis using conformal sensors. Aspects of this disclosure are directed to conformal sensor systems and devices for sensing and analysis of data indicative of body motion, e.g., for such applications as training and/or clinical purposes. According to the representative systems, methods, and devices disclosed in the specification, flexible electronics technology can be implemented as conformal sensors (103) for sensing or measuring motion (including body motion and/or muscle activity), heart rate, electrical activity, and/ or body temperature for such applications as medical diagnosis, medical treatment, physical activity, physical therapy and/or clinical purposes. The conformal sensors can be used for detecting and quantifying impact, and can be used for central nervous system disease monitoring.