ANALOGUES DE L INSULINE STABILISÉS UNE PROTÉASE

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专利权人:

Novo Nordisk A/S

发明人:

申请号：

EP09721144.5

公开号：

EP2254905B1

申请日:

2009.03.13

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to novel insulin analogs comprising mutations at position A14 in the A chain and at positions B27, B28, B29 and B30 in the B chain and exhibiting resistance towards protease； a method for the preparation of such insulin analogs； insulin preparations containing the insulin analogs of the invention； and, a method of treating diabetes mellitus using these insulin analogs.

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