GASPAR, FILIPE,BITTORF, KEVIN, JOHN,KATSTRA, JEFFREY, P
申请号：
NZ57782007
公开号：
NZ577820A
申请日:
2007.12.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a method of fluidized spray drying VX -950, otherwise known as Teleprevir, the method comprising: preparing a liquid feed solution comprising VX-950 atomizing the feed solution upon delivery into the drying chamber of a spray dryer operating in fluidized spray drying mode drying the feed solution in the drying chamber with heated air or a heated gas to obtain a product, wherein larger particles of product separate out, while fines are carried by a stream of air or gas up to the top of the drying chamber and to a cyclone, and re-introducing the fines into the drying chamber, wherein the re-introduced fines can agglomerate with newly formed product to generate an agglomerated product, wherein if the agglomerated product is large enough, it will separate out, if it is not large enough to separate out, the agglomerated product will be carried by convection to the top of the chamber and to the cyclone and re-introduced into the chamber.
