The present invention relates to a pharmaceutical adaptor system. The pharmaceutical adaptor system comprises a syringe assembly having an axial extension and comprising a first end part and a second end part, the first end part having a male tubular projection, the syringe assembly comprising a syringe and a connecting element having a first mechanical connection part, a unit such as a needle, a vial, a catheter or an IV line, and an adaptor providing fluid communication between the syringe and the unit and having a second mechanical connection part configured to engage with the first mechanical connection part in an engagement direction, thereby preventing movement by the first and second connection parts along the axial extension, wherein the adaptor comprises a sealing element configured to receive the male tubular projection. The present invention also relates to a pharmaceutical kit system comprising a pharmaceutical adaptor system according to the present invention.
