CHARI, RAVI V.J.,MILLER, MICHAEL LOUIS,SHIZUKA, MANAMI
申请号：
CA2959630
公开号：
CA2959630A1
申请日:
2015.09.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)- (VI). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.
