Rudolf MOSER,Viola GROEHN,Cristina MUELLER,Roger SCHIBLI,Simon AMETAMEY,Silvan BOSS
申请号：
US16496156
公开号：
US20200306390A1
申请日:
2018.03.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention is directed towards isomerically pure 18F-labelled (6S)- or (6R)-5-methyltetrahydrofolate radiopharmaceuticals, wherein the phenyl group within the folate structure, has been replaced by an 18F-labelled N-heterocycle, for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof.
