前列腺素Ｄ2受體之雜烷基拮抗劑农业专利-农业学术服务平台

发明人:: HUTCHINSON, JOHN HOWARD,哈清恩　约翰　豪尔,哈清恩　約翰　豪爾,SEIDERS, THOMAS JON,塞德斯　汤玛士　琼,塞德斯　湯瑪士　瓊,WANG, BOWEI,王　鲍伊,王　鮑伊,ARRUDA, JEANNIE M.,阿鲁达　洁妮Ｍ,阿魯達　潔妮Ｍ,STEARNS, BRIAN ANDREW,史蒂恩　布莱恩　安德鲁,史蒂恩　布萊恩　安德魯,哈清恩约翰豪尔,哈清恩約翰豪爾,塞德斯汤玛士琼,塞德斯湯瑪士瓊,王鲍伊,王鮑伊,阿鲁达洁妮M,阿魯達潔妮M,史蒂恩布莱恩安德鲁,史蒂恩布萊恩安德魯

摘要：: Described herein are compounds that are antagonists of PGD2receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.本發明描述作為PGD2受體拮抗劑之化合物。本發明亦描述包括本文所述之化合物之醫藥組合物，以及單獨或與其它化合物組合使用該等PGD2受體拮抗劑治療呼吸、心血管及其它PGD2依賴性或PGD2介導之病狀或疾病之方法。