Blockade of gamma-secretase activity to promote myelination by oligodendrocytes

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专利权人:

Trent Alan Watkins

发明人:

Trent Alan Watkins,Ben A. Barres

申请号：

US13066930

公开号：

US08481499B2

申请日:

2011.04.27

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Methods are provided for enhancing myelination. Myelination is enhanced by administration of agents that are inhibitors of γ-secretase. Methods of screening for pharmaceutically active compounds that enhance myelination, and for genes involved in myelination are also provided.

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