BINZ, HANS KASPAR,FORRER, PATRIK,STUMPP, MICHAEL TOBIAS
申请号：
SG2012079687
公开号：
SG185068A1
申请日:
2011.04.29
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
