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INJECTABLE PHARMACEUTICAL COMPOSITION HAVING CONTROLLING ACTIVITY OF pH AND DIVALENT CATION, AND METHOD OF MANUFACTURING THE SAME
专利权人:
发明人:
석현광,김유찬,양석조,한길수,장재석,이동호,장은주,이강식
申请号:
KR1020110017345
公开号:
KR1012978080000B1
申请日:
2011.02.25
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A pharmaceutical composition for injection and a method for manufacturing the same are provided to control pH and/or bivalent cation concentration and to reduce patient's pain. CONSTITUTION: A pharmaceutical composition for injection comprises: a water soluble particle containing alkali earth metal or alloy or compounds of the alkali earth metal; and biocompatible fluid. The pharmaceutical composition has an activity of controlling pH or bivalent cation concentration. The alkali earth meal is Be, Mg, Ca, Sr, Ba, or Ra. The alloy is combination of two or more kinds of Be, Mg, Ca, Sr, Ba, or Ra. The compounds are oxide, hydroxide, sulfur oxides, or chloride of the alkali earth metal. The pharmaceutical composition is used for treating and preventing bone damage, osteoporosis, rheumatitc arthritis, or Paget's disease.본 발명은 외과적 수술 없이 생체 내부에 주입되어, 국부적으로 체내의 pH 및/또는 2가 양이온의 농도를 변화시킴으로써 골다공증, 류마티스 관절염 등의 골질환과 기타 국부적 pH 및/또는 Mg 이온의 농도 조절과 관련된 질환의 예방 또는 치료가 가능한 주입용 약학 조성물 및 이의 제조방법에 관한 것이다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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