UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ;TRON - TRANSLATIONALALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANS GUTENBERG-UNIVERSITAT MAINZ GEMENNUTZIGE GMBH;TRON - TRANSLATIONALALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMENNUTZIGE GMBH;BIONTECH AG
The present invention relates to efficient methods for providing antigen-specificlymphoid cells. These lymphoid cells may be used to provide antigen specific Tcellreceptors having a defined MHC restriction and to identify immunologicallyrelevant T cellepitopes. Furthermore, the present invention relates to antigen-specific Tcell receptors andT cell epitopes and their use in immunotherapy.