Andreas Blomqvist,Anna-Karin Alm,Jörgen Edvinsson,Kjell Norèn,Christopher Graae
申请号:
US12865169
公开号:
US08750979B2
申请日:
2008.01.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
An implantable medical device comprises a signal generator for generating a current signal having a frequency in a frequency window slightly less than the β-dispersion frequency of a tissue and applying the signal over the tissue. A signal measurer measures the resulting voltage signal and an impedance parameter is calculated from the applied and measured signal by a parameter determiner. A status monitor monitors the permeability status of cell membranes in the tissue based on this impedance parameter.