MULTIPLE ANTIGEN BINDING MOLECULAR FUSION, PHARMACEUTICAL COMPOSITION, METHOD FOR IDENTIFYING LINEAR EPITOPE, AND METHOD FOR PREPARING MULTIPLE ANTIGEN BINDING MOLECULAR FUSION

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专利权人:

发明人:

Tomoyuki IGAWA,Naoka HIRONIWA,Hiroki KAWAUCHI

申请号：

US15573154

公开号：

US20180125972A1

申请日:

2016.05.13

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A multiple antigen-binding molecule fusion molecule containing a multiple antigen-binding molecule (α) having an immune cell antigen-binding region and a cancer antigen-binding region, a cancer tissue-specific protease-cleavable linker (β), and a masking molecule (γ) containing a polypeptide having the amino acid sequence QDGNE, in which the multiple antigen-binding molecule (α) and the masking molecule (γ) are linked via the cancer tissue-specific protease-cleavable linker (β).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/