Jack ROTH,David STEWART,Charles LU,Ignacio I. WISTUBA,Shaoyu YAN,Maria I. NUNEZ
申请号：
US14480341
公开号：
US20140377339A1
申请日:
2014.09.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method for predicting a subjects response to a TUSC2 therapy is provided. In particular, a subjects response is predicted based on the proportion of cancers cells that are apoptotic. Also provided is a method of treating a subject previously predicted to have a favorable response with a TUSC2 therapy. Methods for treating cancer by administration of a TUSC2 therapeutic in conjunction with an EGFR inhibitor and/or a protein kinase inhibitor are also disclosed. Kits and reagents for use in TUSC2 therapy are provided.
