BROWN DUNCAN,CUNNINGHAM JAMES J,GINDY MARIAN,PICKERING VICTORIA,STANTON MATTHEW G,STIRDIVANT STEVEN M,STRAPPS WALTER
申请号：
IN142/CHENP/2013
公开号：
IN2013CN00142A
申请日:
2013.01.07
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to compounds compositions and methods for the study diagnosis and treatment of traits diseases and conditions that respond to the modulation of CTNNB1 gene expression and/or activity and/or modulate a beta catenin gene expression pathway. Specifically the invention relates to double stranded nucleic acid molecules including small nucleic acid molecules such as short interfering nucleic acid (siNA) short interfering RNA (siRNA) double stranded RNA (dsRNA) micro RNA (miRNA) and short hairpin RNA (shRNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against CTNNB1 gene expression.
