John CALLAN,Anthony MCHALE,Sukanta KAMILA,Keiran LOAGAN
申请号：
US16618227
公开号：
US20200114003A1
申请日:
2018.05.31
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to microbubble complexes for use in methods of sonodynamic therapy which comprise a microbubble attached to or otherwise associated with one or more linking groups, each linking group being bound to at least one sonosensitising agent and at least one chemotherapeutic agent. It further relates to the microbubble complexes themselves and to pharmaceutical compositions which contain them. The invention is particularly suitable for the treatment of deep-sited tumors, in particular pancreatic cancer.
