KRELL, CHRISTOPH MAX,MISUN, MARIAN,NIEDERER, DANIEL ANDREAS,PACHINGER, WERNER HEINZ,WOLF, MARIE-CHRISTINE,ZIMMERMANN, DANIEL,LIU, WEIDONG,STENGEL, PETER J.,NICHOLS, PAUL
申请号:
CA2888474
公开号:
CA2888474A1
申请日:
2013.10.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to processes for preparing 6-(4-bromo-2- fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2- hydroxyethyoxy)-amide, processes for preparing crystallized 6-(4-bromo-2- fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2- hydroxyethyoxy)-amide, and intermediates useful therefore. Also provided herein are pharmaceutical compositions comprising this crystallized compound.