Mohammad Hassan,Walden Malcolm,Hayes Geoffrey Gerard,Whitehouse Jonathon Oliver,Krishnamurthy Thinnayam Naganathan,Vargas Rincon Ricardo Alberto,Danagher Helen Kathleen
申请号：
NZ71908714
公开号：
NZ719087A
申请日:
2014.11.13
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
The present invention relates to the use of prolonged release combinations of hydromorphone hydrochloride and naloxone hydrochloride in a weight ratio corresponding to about 1:2 of hydromorphone HCl:naloxone HCl for the preparation of a medicament for the treatment of pain in a patient, wherein the medicament is formulated for oral administration of hydromorphone hydrochloride in a daily amount corresponding to from and including about 24 mg up to and including about 48 mg of hydromorphone hydrochloride, and naloxone hydrochloride in a daily amount corresponding to from and including about 48 mg up to and including about 96 mg of naloxone hydrochloride.
