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2 ' -FLU0R0-2 ' -DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS
专利权人:
EISAI INC.
发明人:
GREGORY S. HAMILTON,TAKASHI TSUKAMOTO,DANA V. FERRARIS,BRIDGET DUVALL,RENA LAPIDUS
申请号:
HRP20120419
公开号:
HRP20120419T1
申请日:
2012.05.16
申请国别(地区):
HR
年份:
2012
代理人:
摘要:
The present Invention provides certain tetrahidrouridina derived Compounds, Pharmaceutical compositions and Kits comprising such compounds and Methods of Preparation and use of such compuestos.1.A compound of formula I, or a pharmaceutically acceptable salts thereof, where carbon marked with an Asterisk may have a configuration (R) or (S); and where R1 and R2 are independently selected from Hydrogen, and fl u00b7or, where R1 and R2 are not both hidrogeno.2.- a compound of the formula I selected from the group consisting of where each carbon Atom marked with * have a stereochemical Configuration is selected from the group consisting of a configuration (R), a configuration (S) or a mixture of configurations (R) and (S); and its leaves Pharmaceutically aceptables.3. sThe Compound according to claim 2, wherein the compound is the compound 1.Spoj Formule I ili njegova farmaceutski prihvatljiva sol gdje ugljik označen zvjezdicom može imati R ili S konfiguraciju i gdje su R i R fluor Patent sadrži još patentnih zahtjeva
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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