Diagnostic imaging system and method comprising a device for facilitating breast examinations, comprises: at least one hemispherical portion having a convex outer surface and a concave inner surface defining a containment chamber of a breast; means to wear said hemispherical portion positionable at least around the user's torso to hold the hemispherical portion on said breast; and a connecting tube associated with said hemispherical portion to put in fluid communication the containment chamber with a depressurisation source; the hemispherical portion being made of elastic material to be switchable between a compression condition of the breast and a release condition of the breast.