A system for processing medical image data stores high information content volumetric (HICV) data reconstructed from different medical imaging devices. Images normally requiring differing image imaging parameters can instead be created by processing of the HICV data, importantly without access to the original reconstruction algorithms or machine. The invention also allows different medical images to be harmonized for ready comparison or according to a desired image sequence for particular diagnostic purpose without any need to rescan the patient or to enforce cumbersome universal protocol standards.