Jaime del Campo López-Bachiller;Antonio Lorente Bonde-Larsen;Gerardo Gutiérrez Fuentes;Yolanda Fernández Sainz;Celso Sandoval Rodríguez
发明人:
Gerardo Gutiérrez Fuentes,Antonio Lorente Bonde-Larsen,Jaime del Campo López-Bachiller,Celso Sandoval Rodríguez,Yolanda Fernández Sainz
申请号:
US13805828
公开号:
US08765785B2
申请日:
2011.07.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention concerns fumarate salts of solifenacin, as well as pharmaceutical compositions comprising fumarate salts of solifenacin. The invention furthermore concerns a process for preparing solifenacin and salts thereof. The fumarate salt provides improved properties over the known solifenacin salts, especially in terms of its stability. The novel process for its preparation is furthermore improved over known processes for preparing solifenacin in that it provides a higher yield and recovers a greater amount of starting material.