A method of tracking an affected area and a surgical equipment, which is capable of tracing positions of the affected area and the surgical equipment more precisely through a stereo scope by using images of the affected area and the surgical equipment traced in macro scale after tracing the affected area and the surgical equipment in macro scale. The method of tracking an affected area and a surgical equipment, includes a step of macro tracking in which energy emitted from a plurality of markers attached to the affected area and the surgical equipment is sensed to trace positions of the affected are and the surgical equipment a step of image input in which images of the affected area and the surgical equipment that are traced in the step of macro tracking step are captured by the tracking sensor and the images of the affected area and the surgical equipment , which are captured by the tracking sensor, are inputted to a stereo display part of a microscope and a step of micro tracking in which the positions of the affected area and the surgical equipment are traced based on a coordinate of the microscope by using macro images of the stereo display part of the microscope.