Agomelatine cocrystals comprising agomelatine or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide and an organic acid having a solid state at room temperature, are new. An independent claim is included for the preparation of cocrystals. ACTIVITY : Tranquilizer； Hypnotic； Neuroprotective； Antidepressant； Cardiovascular-Gen.； Gastrointestinal-Gen.； CNS-Gen.； Muscular-Gen.； Neuroleptic； Anorectic； Analgesic； Anticonvulsant； Antidiabetic； Antiparkinsonian； Nootropic； Dermatological； Antimigraine； Endocrine-Gen.； Contraceptive； Immunomodulator； Cytostatic. MECHANISM OF ACTION : Melatoninergic system receptor agonist； Hydroxytryptamine receptor antagonist.
