The present invention provides a compound with stronger AMPK (adenosine monophosphate-activated protein kinase) activation effect, and exhibits beneficial effect originated from AMPK activation effect in living bodies, and also presents excellent hypoglycemic and hypolipidemic effects in living bodies. The present invention relates to a hydantoin derivatives represented by general formula (1), or a pharmacologically permissible salt or a hydrate for the same. The present invention may be applied as a human AMPK activation drug and provide effective treatment for lipid metabolism disorder or diabetes.本發明提供一種具有較強之AMPK活化作用且於生物體內表現出源自AMPK活化作用之有利效果的化合物。本發明係關於一種通式(1)所表示之乙內醯脲衍生物或其藥理上所容許之鹽或該等之水合物。[化1]
