BUSBY, Sharon J.,GROSS, Jane A.,NESTOROV, Ivan,MUNAFO, Alain,PAPASOULIOTIS, Orestis,PENA ROSSI, Claudia,VISICH, Jennifer
申请号：
DK08771043
公开号：
DK2167038T3
申请日:
2008.06.13
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
In various embodiments, the present invention provides methods, compositions, dosing, and administration schedules for treatment of autoimmune diseases, including systemic erythematosus (SLE), for example, comprising administering to a patient in need of such treatment a TACI-Ig fusion molecule such as atacicept. In one embodiment, the TACI-Ig fusion molecule is administered in amount sufficient to slow, suppress or inhibit proliferation-inducing functions of BLyS and APRIL, in particular the use of multiple administrations of the fusion molecule at relatively low dose over the course of the treatment.
