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PEPTIDES ANTIGENIQUES DE REJET TUMORAL DERIVES DE LA SPARC, ET MEDICAMENTS QUI LES RENFERMENT
专利权人:
ONCO THERAPY SCIENCE, INC.;KUMAMOTO UNIVERSITY;ONCOTHERAPY SCIENCE, INC.
发明人:
NISHIMURA, YASUHARU,IKUTA, YOSHIAKI,NAKATSURU, SHUICHI
申请号:
CA2655361
公开号:
CA2655361C
申请日:
2007.06.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
It is an objective of the present invention to identify SPARC protein-derivedpeptides that areable to induce human killer T cells and helper T cells having cytotoxicactivity to tumors, and toprovide a means for carrying out a tumor immunotherapy of patients withvarious types of cancersoverexpressing SPARC. The present invention provides a peptide of any of thefollowing:(A) a peptide which consists of the amino acid sequence as shown in any one ofSEQ ID NOS: 1 to3; or(B) a peptide which consists of an amino acid sequence comprising asubstitution or addition of oneor several amino acids with respect to the peptide consisting of the aminoacid sequence as shown inany one of SEQ ID NOS: 1 to 3, and which has capacity to induce cytotoxic(killer) T cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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