PORAMBO, RICHARD J.,ABEYGUNAWARDANA, CHITRANANDA,MUSEY, LUWY KAVUKA,KOSINSKI, MICHAEL J.,CUI, YADONG ADAM,MCHUGH, PATRICK,KONIETZKO, JANELLE
申请号:
CA3074708
公开号:
CA3074708A1
申请日:
2018.09.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.