DAVIES, Gareth Charles Glyndwr,ROBERTS, Scott John
申请号:
SG11202005735S
公开号:
SG11202005735SA
申请日:
2019.02.14
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The present invention relates to methods for the treatment of a bone fracture or bone defect. The invention discloses the effective use of an anti-gremlin-1 antibody to accelerate the healing and bridging of bone tissue in segmental gap defects; and demonstrates that inhibitors of gremlin-1 activity may provide improved therapies for treating or preventing fracture non-union.