COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES农业专利-农业学术服务平台

发明人:: CHATTERJEE, ARNAB,夏特吉雅那伯,夏特吉雅那伯,NAGLE, ADVAIT,奈葛雷艾德维特,奈葛雷艾德維特,PARASELLI, PRASUNA,帕拉赛利普拉苏纳,帕拉賽利普拉蘇納,KONDREDDI, RAVINDER REDDY,康卓狄拉维恩德雷迪,康卓狄拉維恩德雷迪,LEONG, SEH YONG,梁世勇,梁世勇,MISHRA, PRANAB,米席拉波那

摘要：: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.本發明提供式I化合物:或其醫藥學上可接受之鹽、互變異構體或立體異構體,其中變數如本文所定義。本發明進一步提供包含該等化合物之醫藥組合物及使用該等化合物治療、預防、抑制、改善或根除由瘧原蟲寄生蟲引起之疾病(諸如瘧疾)之病理學及/或症狀的方法。