Diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy

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专利权人:

Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechtes;Ruprecht-Karls-Universitat Heidelberg;Universitatsklinikum Heidelberg

发明人:

Giese, Nathalia,Werner, Jens,Buchler, Markus,Giese, Thomas,Daffler, Laurent,Cziepluch, Celina,Rommelaere, Jean,Raykov, Zahari

申请号：

AU2011247360

公开号：

AU2011247360B2

申请日:

2011.04.29

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

Described is a diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy, comprising exposing primary tumor cells from a patient, e.g., tumor cells obtained from a brain tumor or pancreatic cancer, to (i) a parvovirus and/or (ii) a chemotherapeutic agent or radiotherapy, and determining the reduction of the expression or concentration of ISG15.

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