A system and method for increasing confidence, privacy, and efficiency in obtaining in-home urinalysis results is contemplated. A negative-result control is provided in conjunction with a plurality of test cartridges designed to yield results about the test sample in several different regards (e.g., use of selected combinations of drugs and/or alcohol by the test subject, the integrity of the urine sample, the medical or physiological condition(s) of the test subject, etc.). Convenient sample test bins are included to allow for real-time and/or side-by-side comparison of the urine sample test results against a verified, negative result control.