Dale Howard Hreczuk-Hirst,Sanjay Jain,Peter Laing,Gregory Gregoriadis,Ioannis Papaioannou
申请号：
US13650048
公开号：
US09102714B2
申请日:
2012.10.11
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.
