invention holde Leah Burke Gourmet 411gr-6 was created for the antimicrobial activity of plant pathogens in having relates to a novel antimicrobial active substance of the phenazine series, more specifically, the present invention is described by formula (1) 5 to produce the above strain, 10-dihydro-4, 9-dihydroxy pen coma who ester (5 , 10-dihydro-4, 9-dihydroxyphencomycin methyl ester, the novel compounds) and the pen coma who is described by the following formula 3 (phencomycin, CAS # 146615-53-4), 4- hydroxy-pen coma who is (4-hydroxyphencomycin, New compounds), 4-hydroxy-pen coma who methyl ester (4-hydroxyphencomycin methyl ester, CAS # 79417-76-8) and a preparation method thereof. New phenazine antibiotics of the present invention Station germs pepper, cucumber anthracnose fungus, Botrytis bacteria, fruit trees and crops such as rice blast fungus economically at low concentrations to inhibit spore germination and mycelial growth of plant pathogens and causing serious damage to the There may be able to provide low-toxic and eco-friendly new plant disease control agents.본 발명은 버크홀데리아 그루메 411gr-6이 생성하는 식물병원균에 대해 항균활성을 갖는 페나진 계열의 신규 항균활성물질에 관한 것으로, 더욱 상세하게, 본 발명은 상기 균주가 생산하는 화학식 1로 기재되는 5, 10-다이하이드로-4, 9-다이하이드록시펜코마이신 메틸 에스터 (5, 10-dihydro-4, 9-dihydroxyphencomycin methyl ester, 신규 화합물)와 화학식 3으로 기재되는 펜코마이신 (phencomycin, CAS# 146615-53-4), 4-하이드록시펜코마이신 (4-hydroxyphencomycin, 신규 화합물), 4-하이드록시펜코마이신 메틸 에스터 (4-hydroxyphencomycin methyl ester, CAS# 79417-76-8) 및 이의 제조 방법을 포함한다. 상기 본 발명의 신규 페나진 항생물질은 고추 역병균, 오이 탄저병균, 잿빛곰팡이병균, 벼 도열병균 등 과수 및 농작물에 경제적으로 심각한 피해를 입히는 식물병원균의 포자 발아 및 균사 생장을 낮은 농도에서 저해시킬 수 있어 저독성이고 친환경적인 새로운 식물병 방제제를 제공할 수 있다.
