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COMPOSE D'AMIDE D'ACIDE ACETIQUE HETEROCYCLIQUE
专利权人:
ASTELLAS PHARMA INC.
发明人:
SHIRAKI, RYOTA,TOBE, TAKAHIKO,KAWAKAMI, SHIMPEI,MORITOMO, HIROYUKI,OHMIYA, MAKOTO
申请号:
CA2909783
公开号:
CA2909783A1
申请日:
2014.04.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
[Problem] To provide a compound of formula (I) that is useful as a dopamine D1 receptor positive allosteric modulator (D1 PAM). [Solution] The inventors studied a compound that has a dopamine D1 receptor positive allosteric modulating action and is useful as an active ingredient for a pharmaceutical composition for preventing and/or treating cognitive dysfunction, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug dependence, etc., have verified that a heterocyclic acetic acid amide compound has a dopamine D1 receptor positive allosteric modulating action, and have completed the present invention. This heterocyclic acetic acid amide compound has a dopamine D1 receptor positive allosteric modulating action and may be used as a preventive and/or therapeutic agent for cognitive dysfunction, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug dependence, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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