Methods and compositions for reducing bladder spasms are disclosed. The methods comprise administering to a subject in need thereof a pharmaceutical composition comprising an effective amount of acetaminophen and an effective amount of at least one non-steroidal anti-inflammatory drug (NSAID). In another embodiment, a method for reducing bladder spasms comprising administering to a subject in need thereof a pharmaceutical composition comprising an effective amount of at least one prostaglandin (PG) pathway inhibitor, wherein the at least one PG pathway inhibitor is not acetaminophen or an NSAID.本發明揭示用於降低膀胱痙攣之方法及組成物。該方法包含對有需要的個體投予一醫藥組成物,該醫藥組成物係包含一有效量的乙醯胺酚(acetaminophen)以及一有效量的至少一非類固醇抗發炎藥物(non-steroidal anti-inflammatory drug,NSAID)。在另一實施態樣中,一種用於降低一個體之膀胱痙攣的方法,該方法包含對有需要的個體投予一醫藥組成物,該醫藥組成物係包含一有效量的至少一前列腺素(prostaglandin,PG)途徑抑制劑,其中該至少一PG途徑抑制劑係非乙醯胺酚或一NSAID。
