FORMULATION DE MEDICAMENT A RETENTION GASTRIQUE ET SYSTEMES D'ADMINISTRATION ET LEUR PROCEDE DE PREPARATION A L'AIDE DE CARBONATE DE CALCIUM FONCTIONNALISE
GERARD, DANIEL E.,SCHOELKOPF, JOACHIM,GANE, PATRICK A. C.,EBERLE, VERONIKA ANNA,ALLES, RAINER,PUCHKOV, MAXIM,HUWYLER, JORG
申请号：
CA2885971
公开号：
CA2885971C
申请日:
2013.10.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.
