Composition comprising a Chimeric POLYPEPTIDE WITH factor VIII activity, and use of the composition for preventing, reducing or treating a Bleeding Disorder, such as Hemophilia.
BIOVERATIV THERAPEUTICS INC.;BIOGEN IDEC HEMOPHILIA INC.
发明人:
PIERCE GLENN,JIANG HAIYAN,PETERS ROBERT,DUMONT JENNIFER A.,LOW SUSAN,LUK ALVIN,MCKINNEY BYRON,OTTMAR MATT,SOMMER JURG,NUGENT KAREN,LI LIAN,BITONTI ALAN J
申请号：
CL2014000024
公开号：
CL2014000024A1
申请日:
2014.01.07
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof)； methods of administering chimeric and hybrid polypeptides comprising Factor VIII； chimeric and hybrid polypeptides comprising Factor VIII； polynucleotides encoding such chimeric and hybrid polypeptides； cells comprising such polynucleotides； and methods of producing such chimeric and hybrid polypeptides using such cells.COMPOSICIÓN QUE COMPRENDE UN POLIPÉPTIDO QUIMÉRICO QUE TIENE ACTIVIDAD DE FACTOR VIII, Y USO DE LA COMPOSICIÓN PARA PREVENIR, DISMINUIR O TRATAR UNA AFECCIÓN DE SANGRADO, TAL COMO HEMOFILIA.
