Composition comprising a Chimeric POLYPEPTIDE WITH factor VIII activity, and use of the composition for preventing, reducing or treating a Bleeding Disorder, such as Hemophilia.
BIOVERATIV THERAPEUTICS INC.;BIOGEN IDEC HEMOPHILIA INC.
发明人:
PIERCE GLENN,JIANG HAIYAN,PETERS ROBERT,DUMONT JENNIFER A.,LOW SUSAN,LUK ALVIN,MCKINNEY BYRON,OTTMAR MATT,SOMMER JURG,NUGENT KAREN,LI LIAN,BITONTI ALAN J
申请号:
CL2014000024
公开号:
CL2014000024A1
申请日:
2014.01.07
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.COMPOSICIÓN QUE COMPRENDE UN POLIPÉPTIDO QUIMÉRICO QUE TIENE ACTIVIDAD DE FACTOR VIII, Y USO DE LA COMPOSICIÓN PARA PREVENIR, DISMINUIR O TRATAR UNA AFECCIÓN DE SANGRADO, TAL COMO HEMOFILIA.