The present invention relates to a transdermal absorption agent comprising donepezil for treatment of dementia and, more particularly, to a transdermal absorption agent for treatment of dementia, the agent comprising: (a) donepezil as an effective ingredient； (b) propylene glycol monocaprylate as a solubilizer； and (c) a styrene-isoprene-styrene block copolymer as an adhesive base material. The transdermal absorption agent for treatment of dementia according to the present invention has weak skin irritation and excellent skin permeability simultaneously.
