AKMAN, Hasan, Orhan,DIMAURO, Salvatore,KAKHLON, Or,MIGUEL, Weil
申请号：
EP17736394
公开号：
EP3400025A4
申请日:
2017.01.06
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The current invention is a method of preventing and treating certain diseases by preventing the synthesis and/or breakdown of glycogen by the administration of an agent, guaiacol. Diseases that can be prevented and treated by the administration of guaiacol include but are not limited to glycogen storage disease type IV (GSD-IV), adult polyglucosan body disease (APBD), and Lafora disease (LD). The invention also includes methods and tools for screening for agents that prevent and treat these diseases as well as basic research, specifically in the form of cells and cell lines that produce detectable polyglucosan.
