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Influenza virus vaccine composition and method of use thereof
专利权人:
バイカル インコーポレイテッド
发明人:
ルーク,キャサリン,ビラルタ,エイドリアン,ブロシュ,メアリー ケー.,ギール,アンドリュー,エバンス,トーマス ジー.,ヒメネス,グレッチェン エス.,ルーク,キャサリン,ビラルタ,エイドリアン,ブロシュ,メアリー ケー.,ギール,アンドリュー,エバンス,トーマス ジー.,ヒメネス,グレッチェン エス.
申请号:
JP2007527348
公开号:
JP5331340B2
申请日:
2005.05.18
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo. The IV protein (in purified form or in the form of an inactivated IV vaccine) is also administered in an immunologically effective amount.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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