FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to organic chemistry, namely to new quinolin-4-one derivatives of formula (1) or to its pharmaceutically acceptable salt, wherein R1 represents: (1) hydrogen, (2) C1-C6 alkyl, (35) carbamoyl-C1-C6 alkyl optionally containing morpholinyl-C1-C6 alkyl, or (36) phosphonoxy-C1-C6 alkyl optionally containing one or two C1-C6 alkyl groups on a phosphonoxy group； R2 represents: (1) hydrogen or (2) C1-C6 alkyl； R3 represents phenyl, thienyl or furyl, wherein a phenyl ring presented by R3, can be substituted by one C1-C6 alkoxy group； R4 and R5 are bound to form a group presented by any of the following formulas: , , , , , , or a group presented by the following formula: a group optionally containing one or more substitutes specified in a group consisting of C1-C6 alkyl groups and oxogroups； R6 represents hydrogen； and R7 represents C1-C6 alkoxy group. The invention also refers to a pharmaceutical composition based on the compound of formula , to a preventive and/or therapeutic agent based on the compound of formula (1), using the compound of formula (1), a method for preparing the compound of formula , as well as to specific compounds.EFFECT: there are prepared new quinolin-4-one derivatives effective in treating neurodegenerative diseases, diseases caused by neurological dysfunction, or diseases caused by mitochondrial dysfunction.18 cl, 1 tbl, 257 exИзобретение относится к области органической химии, а именно к новым производным хинолин-4-она формулы (1) или к его фармацевтически приемлемой соли, где R1 представляет собой: (1) водород, (2) С1-С6 алкил, (35) карбамоил-С1-С6 алкил, необязательно содержащий морфолинил-С1-С6 алкил, или (36) фосфонокси-С1-С6 алкил, необязательно содержащий одну или две С1-С6 алкильные группы на фосфоноокси группе； R2 представляет собой: (1) водород или (2) С1-С6 алкил； R3 представляет собой фенил, тиенил или фурил, где фенильное кольцо, представленное R3, может быть замещено одной
