LAROSA, GREGORY J.,HORVATH, CHRISTOPHER,NEWMAN, WALTER,JONES, S. TARRAN,O'BRIEN, SIOBHAN,O'KEEFE, THERESA
申请号：
CA2399080
公开号：
CA2399080C
申请日:
2001.02.02
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to a humanized antibody or functional fragmentthereof which binds to a mammalian (e.g., human) CC-chemokine receptor (2)(CCR2) or a portion of the receptor and blocks binding of a ligand to thereceptor. The invention further relates to a method of inhibiting theinteraction of a cell bearing mammalian CCR2 with a ligand thereof, and to useof the antibodies and fragments in therapeutic, prophylactic and diagnosticmethods.
