ASCLEPIX THERAPEUTICS, LLC;The Johns Hopkins University
发明人:
Niranjan B. Pandey,Adam Mirando,Aleksander S. Popel,Jordan J. Green
申请号：
US16336777
公开号：
US20190225670A1
申请日:
2017.10.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention in various aspects and embodiments, involves methods for treating Tie2-related vascular permeability by administering one or more collagen IV-derived biomimetic peptides and involves compositions for treating Tie2-related vascular permeability comprising one or more collagen IV-derived biomimetic peptides. Such peptides can promote the Tie2 agonist activities of Angiopoietin 2 (Ang2), thereby stabilizing vasculature and/or lymphatic vessels.
