DELIVERY OF CAS9 VIA ARRDC1-MEDIATED MICROVESICLES (ARMMS)

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专利权人:

发明人:

Quan Lu,Qiyu Wang,Stanley N. Cohen

申请号：

US14929177

公开号：

US20160206566A1

申请日:

2015.10.30

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Methods, systems, compositions and strategies for the delivery of WW domain-containing fusion proteins into cells in vivo, ex vivo, or in vitro via ARMMs are provided. Methods, systems, compositions and strategies for the delivery of Cas9 proteins and/or Cas9 variants into cells in vivo, ex vivo, or in vitro via fusion to ARMM associated proteins (e.g., ARRDC1 or TSG101) are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/