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Use of 7-chloro-N, N, 5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino [4,5-b] indole-1-acetamide as a biomarker of levels of peripheral benzodiazepine receptors
专利权人:
SANOFI;COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIESALTERNATIVES
发明人:
BENAVIDES, JESUS,BOUTIN, HERVE,CASTEL, MARIE-NOELLE,DAMONT, ANNELAURE,DOLLE, FREDERIC,HANTRAYE, PHILIPPE,MARGUET, FRANK,ROONEY, THOMAS,RIVRON, LUC,TAVITIAN, BERTRAND,THOMINIAUX, CYRILLE
申请号:
ES09760593
公开号:
ES2452665T3
申请日:
2009.10.27
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Use of 7-chloro-N, N, 5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino [4,5-b] indole-1-radiolabeled acetamide as a biomarker for detection, in an individual, from the levels of the peripheral benzodiazepine receptor (PBR) associated with normal and pathological conditions, in which the radiolabel is chosen from carbon-11, radiohalogens and radiometals.Uso de 7-cloro-N,N,5-trimetil-4-oxo-3-fenil-3,5-dihidro-4H-piridazino[4,5-b]indol-1-acetamida radiomarcada comobiomarcador para la detección, en un individuo, de los niveles del receptor periférico de benzodiazepina (PBR)asociados con estados normales y patológicos, en el que la radiomarca se elige entre carbono-11, radiohalógenos yradiometales.
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