INNOVATIVE CELLULAR THERAPEUTICS CO., LTD.;ZHEJIANG UNIVERSITY
发明人:
LEI XIAO,CHENGFEI PU,ZHAO WU,LINRONG LU
申请号:
US16568799
公开号:
US20200078403A1
申请日:
2019.09.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Embodiments of the present disclosure include a method for treating Systemic Lupus Erythematosus (SLE) using CD19 CAR T cells. The method includes administering to the human patient a pharmaceutically effective amount of a population of T cells of the human patient that express a chimeric antigen receptor (CAR) that comprises the amino acid sequence of, e.g., SEQ ID NO: 23.